Megestrol acetate ( Megestrol Acetate; NSC 71423; SC-10363 )

Catalog No. M15210 CAS No. 595-33-5

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HNMR

HPLC

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Product Name

Megestrol acetate
Note

Research use only, not for human use.
Brief Description

Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general.
Description

Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast Y. Megestrol acetate has been approved to treat anorexia and cachexia.
Synonyms

Megestrol Acetate; NSC 71423; SC-10363
Pathway

Endocrinology/Hormones
Target

Estrogen Receptor/ERR
Recptor

ER; Glucocorticoid Receptor
Research Area

Endocrinology
Indication

——

CAS Number

595-33-5
Formula Weight

384.51
Molecular Formula

C24H32O4
Purity

>98%(HPLC)
Solubility

Ethanol: 15 mg/mL (39.01 mM); DMSO: 33 mg/mL (85.82 mM)
SMILES

CC(O[C@]1(C(C)=O)CC[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Chemical Name

(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

1.Vadivelu S, et al. J Neurosurg. 2010 May;112(5):920-4.

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